Alzheimer’s Disease is a very prominent condition that is being studied extensively by researchers worldwide. However, like many conditions of the brain, there is no exclusive cause of Alzheimer’s that applies to every case that scientists have identified. There can be similarities, though, and those help scientists understand the disease and draw conclusions from new data that comes in.
For example, scientists have identified abnormal deposits of proteins that form amyloid plaques and tau tangles on and inside neurons in all parts of the brain in many cases of Alzheimer’s (2024 Alzheimer’s disease facts and figures, Alzheimer’s Association). However it is only a common similarity and not classified as a cause.
Factors that Increase the Risk of Developing Alzheimer’s Disease
There might not be one cause of Alzheimer’s Disease, but there are different factors that can increase the risk of developing the condition. These can include:
Age
As the body ages, it changes as well. The brain experiences age-related changes too like shrinkage, a shift in the level of chemicals it delivers for cognitive functions, and a decrease in blood flow (How the Aging Brain Affects Thinking, National Institute on Aging). Those with Alzheimer’s Disease have higher numbers of damaged neurons, which is not normal. This disrupts communication in the brain which then affects memory, language, reasoning, and social behavior (What Happens to the Brain in Alzheimer’s Disease?, National Institute of Aging).
Genetics and Family History
There isn’t a single gene that causes Alzheimer’s Disease. Instead, the condition is influenced by a combination of multiple genes, lifestyle, and environmental factors. While individuals who develop Alzheimer’s Disease do not always have someone in their family who also had the condition, if one family member had it, you are at a higher risk of developing the disease as well (What Causes Alzheimer’s Disease?, National Institute of Aging).
Head Injuries
Chronic inflammation of the brain that can sometimes result from head injuries have been linked to developing Alzheimer’s Disease (Alzheimer’s Association). This is often because of past injuries from car accidents or contact sports like football, rugby, boxing, and hockey.
Other Health Conditions
According to research, there is evidence that some medical conditions and lifestyle factors can contribute to a higher risk of Alzheimer’s Disease. These include medical conditions like:
- Heart Disease
- Stroke
- High Blood Pressure
- Hearing Loss
- Depression
- Traumatic Brain Injuries
Lifestyle Factors
Lifestyle factors are an important part of health in general. When it comes to Alzheimer’s Disease, overall health also plays a part. You can reduce your risk of Alzheimer’s by maintaining brain, body, and heart health (What Causes Alzheimer’s Disease?, National Institute of Aging). You might be increasing your risk with factors such as:
- Physical inactivity
- Obesity or an unhealthy diet
- Heavy alcohol use
- Poor sleep habits
- Social isolation
- Lack of mental stimulation